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Natural Product Libraries

This listing is for informational purposes only and is not a comprehensive listing. The National Center for Complementary and Integrative Health (NCCIH) does not guarantee the availability or content of any of the listed libraries. Acceptance of any such terms is at the sole discretion of the prospective user, and as agreed to between the prospective user and the library administrator. Inclusion on this listing does not indicate NCCIH’s approval of such terms, and does not constitute an endorsement or recommendation of any specific commercial products, process, service, manufacturer, or company by the U.S. Government, or specifically by the National Institutes of Health or NCCIH.

Library Name and/or CompanyContact InformationMaterials Available in the LibraryInformation About the Materials

Natural compounds from microbial and terrestrial sourcesInformation not provided for listing; consult with company.
Comprehensive access to nature’s chemical diversity: plants, fungi, microbial strains (11,500 pure natural compounds derived from plant and microbial sources; 63,000 purified fractions derived from distinct microbial extracts; 21,200 pre-purified extracts including samples derived from microbial extracts, plants and mushroom fruit bodies; 40,000 distinct strains from bacterial and fungal genetic sources)Information not provided for listing; consult with company.

High purity metabolites from bacteria and fungiProduct name, synonym, CAS number, molecular formula, molecular weight, description of chemical, and biological characteristics

Biosortia makes available rare small molecules (SMs) made from microorganisms (bacteria, fungi, archaea, and viruses) in natural microbiomes. We specialize in the “hard to obtain” or large quantities by special request for rare SMs.Chemical structures and biological activities of the compounds are available.
Phytotitre Natural Product Library



Unique focus on plants with a history of use as traditional medicines or association with reduced risk of disease in studies of dietary epidemiology aims to maximize accessibility and hit rate for groups seeking to screen natural product libraries. 800 extracts in DMSO, microplate format.Information on traditional ethnomedicinal use or other rationale for inclusion in the library is provided in electronic format with plate maps.
More than 15,000 natural extracts from plant, animal, marine, and microbial sources.The natural extract library is available for screening in frozen 96-well plates, in standard solutions (DMSO, 10 mg/ml).
Natural Compound Libraries

Wide selection of high-quality reference standards suited for the natural products industry focusing on dietary supplements, food and beverage, skin care, and pharmaceutical markets. Has been developed with a key balance of known active and well-characterized phytochemicals in combination with unusual and difficult-to-isolate compounds.Neat inventory immediately available. Botanical extract library, produced through a proprietary extraction process combining both serial and parallel techniques to decrease false negatives and maximize screening hits; 1,200 are extensively characterized; 2,550 total fractions; derived from 425 plants and plant parts; cross-fraction synergy preserved.

Samples derived from marine and terrestrial microorganisms and plantsInformation not provided for listing; consult with company.

Natural products from cyanobacteriaLibraries in the form of crude extracts, prefractionated extracts, and pure compounds in 96 well MTPs ready to screen. Bioactivity data for all library formats available on request.
Developmental Therapeutics Program,
the National Cancer Institute Natural Products Repository, National Institutes of Health
One of world’s most comprehensive collections of natural products. More than 230,000 crude extracts from plant, marine and microbial sources from countries around the world; over 400 purified natural product compounds; traditional Chinese medicinal plant extracts library.No cost for materials; only shipping fee is charged; in both 96- and 384-well formats ready for HTS screens.
Greenpharma Natural Compound

Diverse and pure compounds from natural resources including plants, bacteria and other terrestrial sourcesElectronic file containing the structure, the name, the position of each product in the microplate, examples of natural sources producing the compounds, and calculated physico-chemical descriptors

Sujata Moton
121 Stryker Lane
Hillsborough, NJ 08844
Offers natural products, herbal and nutritional products, flavonoids, and coumarins. Can make a custom library.All of the natural products are extracted. Products are of high purity.
InterBioScreenscreen@ibscreen.comSynthetic and natural compounds and their derivatives. Synthetic compounds with maximal diversity and natural compounds isolated from various natural sources such as plants, fungi, molds, insects, marine organisms, or produced by total synthesis of natural products and/or derivatives of natural products obtained by their chemical modification.Information not provided for listing; consult with company.
More than 200,000 microbial and plant extracts (fractions available), purified compounds, and microbial strains from large and diverse sourcesInformation not provided for listing; consult with company.

Marine microbes from sediment water and associated invertebrate and plant tissuesInformation not provided for listing; consult with company.

Purified natural products sourced from plant, animal, marine and microbial sources, as well as natural product synthetic equivalents for researchA unique collection of 3500+ natural products and natural product synthetic equivalents encompassing saccharides, glycosides, phenylpropanoids, quinones, flavonoids, terpenoids, steroids, alkaloids, phenols, acids and aldehydes. All natural products have clear sources and structural classifications. Detailed information include product name, CAS number, structure, formula weight, source type, structure type, solubility, SMILES, biological activity, clinical information, etc.

+34 958 993 965
One of the world´s largest libraries of microbial-derived natural products. More than 200,000 extracts from marine and terrestrial microorganisms from the most diverse environments all around the world.The library is organized in modules robotically integrated for faster and efficient screening and is available for testing at MEDINA or at external partner site.
MicroSource Discovery

Approximately 75% of the collection encompasses: alkaloids (16%), flavanoids (12%), sterols/triterpenes (12%), diterpenes/sesquiterpenes (10%), benzophenones/chalcones/stilbenes (10%), limonoids/quassinoids (9%), and chromones/coumarins (6%). The remainder of the collection includes quinones/quinonemethides, benzofurans/benzopyrans, otenoids/xanthones, carbohydrates, and benztropolones/depsides/depsidones.Collection of 800 compounds, all are fully characterized according to literature reports and meet criteria of a minimum of 95% purity. Compounds selected on the basis of structural and chemical class.
Natural Product Discovery Center, Scripps

Natural products of bacterial origin, as MPLC fractions and crude extractsStructures of the pure compounds, HPLC chromatograms of the fractions and extracts, geographic location and ecological environment of the strains from which the fractions and crude extracts were prepared, and very limited activity information associated with them
Natural Products Discovery Core,
University of Michigan

Metadata enabled (chemical and genetic profile) 45,000 NPEs (and still growing) from diverse marine/terrestrial actinomycetesNPEs from Asia-Pacific, the Middle East, North and South America, and the Antarctic. The library is configured in HTS format (94/384/1536 well) for scientific exploration (academia/industry). Internal HTS facility, Center for Chemical Genomics.
NatureBank, Griffith Institute for Drug Discovery, Griffith

Rohan Davis
Marine- and plant-derived lead-like enhanced extract (>18,000), fraction (>90,000) and pure compound (>100) librariesSamples have been processed into three unique libraries: a lead-like extract library, a lead-like fraction library, and a pure compound library, which are ready for screening to discover new bioactive compounds in a range of applications (e.g., biomedical, agrochemical, nutraceutical). Also holds more than 30,000 archived biota samples. These libraries represent the unique biodiversity of Australia, which translates into novel chemical diversity.

Natural compounds/phytochemicals for researchInformation not provided for listing; consult with company.

877-796-6397 (U.S. and Canada only)
Purified natural products for researchA unique collection of 2,228 natural products for high-throughput screening and high-content screening. Includes quinones, flavonoids, terpenoids, alkaloids, saponins, medicine food homology compounds, human endogenous metabolite compounds and natural organic compounds. Structurally diverse, bioactive, and cell permeable; rich documentation with structure; NMR and HPLC validated ensure high purity.

Purified natural products and derivatives thereof from natural sources like plants, fungi, bacteria, and sea organismsMolecular structure and molecular formula, name of the natural product (if the compound is a derivative, the name of the parent structure and “derivative of” is mentioned, e.g., “dubamine derivative of”), name of the source of the natural product (e.g., “isolated from haplophullum latifolium”), and available stereochemical information
TargetMol Chemicals, Inc.
Natural Product Library for HTS

Purified natural products sourced from plant, animal, microorganism, marine species, etc. The collection of this library encompasses alkaloids, flavonoids, glycosides, phenols, phenylpropanoids, quinones, saccharides, steroids, and terpenoids.A unique collection of 4,533 compounds with highly customizable option for high-throughput screening and high-content screening. Detailed information including product name, molecular structure, CAS number, molecular formula, molecular weight, source, bioactivity, status, and trade name.

Compounds sourced from plants, bacteria, fungus, and animalsCommon natural sources and reference information is available for natural product library records.

Please send all requests for inclusion of new libraries and any changes in information for libraries currently listed to Dr. Craig Hopp. Submissions should be limited to a word count of 50 or less.