Expanding Translationally Relevant Chemical Space: Insights Into Natural Product Resources, Technologies, and Mechanisms (Two-Part Webinar Series)—April 28, 2023
Date: April 28, 2023 - 1:00 p.m. ET to 3:00 p.m. ET
Virtual
Event Description
This two-part Hot Topics Webinar Series highlighted emerging trends in natural products research. Leading experts in the natural products field touched on topics in organic structure analysis, metabologenomics, venomics, high-throughput phenotypic screening, electron microscopy techniques, host microbe interactions, and structural biology. Part One took place on March 6, and covered natural product research resources enabling discovery and development of natural products as lead compounds and research tools.
Part Two took place on April 28, 2023. This webinar focused on applications of emerging research technologies to elucidate the mechanism of action of bioactive natural products.
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Agenda
1:00–1:10 p.m. | Welcome and Introductory Remarks
Natural products research in the context of the 2021–2025 strategic plan, nutritional interventions, and whole person health
- Emmeline Edwards, Ph.D., Director, Division of Extramural Research, National Center for Complementary and Integrative Health (NCCIH)
- Patrick C. Still, Ph.D., Program Director, NCCIH Basic and Mechanistic Research Branch
1:10–1:25 p.m. | Electron Microscopy Techniques To Enable Characterization of Complex Natural Products
- Hosea M. Nelson, Ph.D., Professor of Chemistry, Division of Chemistry and Chemical Engineering, Caltech
1:25–1:40 p.m. | Structural Insights Into Ion Channel Detection of Physical and Chemical Stimuli
- Melinda Diver, Ph.D., Assistant Member, Structural Biology Program, Sloan Kettering Institute
1:40–1:55 p.m. | Chemical Correlations Between Gut Microbes and Host Responses
- Chelsi D. Cassilly, Ph.D., Postdoctoral Fellow, Clardy Laboratory, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
1:55–2:10 p.m. | Q & A
- D. Craig Hopp, Ph.D., Deputy Director, NCCIH Division of Extramural Research
2:10–2:40 p.m. | National Institutes of Health (NIH) Institute and Center Priorities in Natural Products Research
Perspectives on webinar themes and natural products research in the context of various NIH Institute and Center priorities
- Yali Fu, Ph.D., Program Director, Preclinical Testing Grants Branch, Developmental Therapeutics Program, National Cancer Institute
- D.P. Mohapatra, Ph.D., Program Director, Pain, Somatosensation, and Glia/Neuroimmune Biology, National Institute of Neurological Disorders and Stroke
- Michelle R. Bond, Ph.D., Program Director, Division of Pharmacology, Physiology and Biological Chemistry, National Institute of General Medical Sciences
- Ryan Ranallo, Ph.D., Program Director, Co-Chair, Trans-NIH Microbiome Working Group, National Institute of Allergy and Infectious Diseases
2:40–2:55 p.m. | Q & A
2:55–3:00 p.m. | Wrap-Up and Closing Remarks
- Patrick C. Still, Ph.D., Program Director, NCCIH Basic and Mechanistic Research Branch