An official website of the United States governmentExpanding Translationally Relevant Chemical Space: Insights Into Natural Product Resources, Technologies, and Mechanisms (Two-Part Webinar Series)—March 6, 2023
Event Description
This two-part Hot Topics Webinar Series highlighted emerging trends in natural products research. Leading experts in the natural products field touched on topics in organic structure analysis, metabologenomics, venomics, high-throughput phenotypic screening, electron microscopy techniques, host-microbe interactions, and structural biology.
Part One took place on March 6, 2023, and covered natural product research resources enabling discovery and development of natural products as lead compounds and research tools.
Part Two took place on April 28, 2023. This webinar focused on applications of emerging research technologies to elucidate the mechanism of action of bioactive natural products. View agenda for the second webinar.
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Draft Agenda
2:00–2:10 p.m. | Welcome and Introductory Remarks
Natural products research in the context of the 2021–2025 strategic plan, nutritional interventions, and whole person health
- David Shurtleff, Ph.D., Deputy Director, National Center for Complementary and Integrative Health (NCCIH)
- Patrick C. Still, Ph.D., Program Director, NCCIH Basic and Mechanistic Research Branch
2:10–2:25 p.m. | Discovery and Development of Natural Products and the National Cancer Institute (NCI) Natural Product Collection
- Barry O’Keefe, Ph.D., Chief, Natural Products Branch, Division of Cancer Treatment and Diagnosis, NCI
2:25–2:40 p.m. | High-Throughput Functional Annotation of Natural Products Using Integrated Activity Profiling
- Roger Linington, Ph.D., Professor, Canada Research Chair in High-Throughput Screening and Natural Products Discovery, Simon Fraser University
2:40–2:55 p.m. | Comparative Functional Genomics in the Discovery of New Peptide Research Tools (Tentative Topic)
- Mandë Holford, Ph.D., Associate Professor, Department of Chemistry and Biochemistry, City University of New York; Research Associate, Sackler Institute for Comparative Genomics, American Museum of Natural History
2:55–3:10 p.m. | Q & A
- D. Craig Hopp, Ph.D., Deputy Director, NCCIH Division of Extramural Research
3:10 –3:40 p.m. | National Institutes of Health (NIH) Institute and Center Priorities in Natural Products Research
Perspectives on webinar themes and natural products research in the context of various NIH Institute and Center priorities
- Yali Fu, Ph.D., Program Director, Preclinical Testing Grants Branch, Developmental Therapeutics Program, NCI
- D.P. Mohapatra, Ph.D., Program Director, Pain, Somatosensation, and Glia/Neuroimmune Biology, National Institute of Neurological Disorders and Stroke
- Michelle R. Bond, Ph.D., Program Director, Division of Pharmacology, Physiology and Biological Chemistry, National Institute of General Medical Sciences
- Ryan Ranallo, Ph.D., Program Director, Co-Chair, Trans-NIH Microbiome Working Group, National Institute of Allergy and Infectious Diseases
3:40–3:55 p.m. | Q & A
3:55–4:00 p.m. | Wrap-Up and Closing Remarks
- D. Craig Hopp, Ph.D., Deputy Director, NCCIH Division of Extramural Research