Grant Policies and Guidance

Research grants are subject to a variety of policy requirements. Below are highlights of policy resources and announcements specific to NIH and NCCIH. The NIH Grants Policy Statement and the NIH Guide to Grants and Contracts contain the comprehensive grants administration policies, laws, and regulations for NIH research.


  • Notices of NIH Policy Changes Notices published in the NIH Guide for Grants and Contracts can supercede information in the NIH Grants Policy Statement and/or provide reminders to applicants and grantees. NIH incorporates these notices into the annual update of the NIH Grants Policy Statement.
  • NIH Grants Policy Statement

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NCCIH Clinical Research Toolbox

Grant Policies

NCCIH Policies

Progress Reports

Clinical Research and Human Subjects

Human subjects research is research involving a living individual, or about whom an investigator conducting research obtains: data through intervention or interaction with the individual; or identifiable private information.*

Data and Safety Monitoring

Resources for Clinical Investigators

Animal Studies, Care, and Protection Policies

International Studies