Skip to main content

Know the Science: How Medications and Supplements Can Interact

How Medications and Supplements Can Interact


Many Americans take dietary supplements along with prescription or over-the-counter medications.

Sometimes, taking medications and supplements together may have unintended effects, including:

  • Increasing the medication’s effects
  • Decreasing the medication’s effects
  • Interacting with the medication in harmful ways

That’s why you should talk with your health care providers about all dietary supplements and medications you take.

Learn more about talking with your providers, the different ways supplements and medications can interact, and how to read and understand labels on supplements—then test your knowledge.